MedKoo Cat#: 531883 | Name: GSK575594A
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

GSK575594A is a GPR55-selective agonist.

Chemical Structure

GSK575594A
GSK575594A
CAS#909418-68-4

Theoretical Analysis

MedKoo Cat#: 531883

Name: GSK575594A

CAS#: 909418-68-4

Chemical Formula: C24H23F2N3O3S

Exact Mass: 471.1428

Molecular Weight: 471.52

Elemental Analysis: C, 61.13; H, 4.92; F, 8.06; N, 8.91; O, 10.18; S, 6.80

Price and Availability

Size Price Availability Quantity
25mg USD 850.00 2 Weeks
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Related CAS #
No Data
Synonym
GSK575594A; GSK 575594A; GSK-575594A.
IUPAC/Chemical Name
[4-(4-amino-2-fluorophenyl)piperazin-1-yl]-[2-(4-fluorophenyl)-5-methylsulfonylphenyl]methanone
InChi Key
DAPKZHQMEQRNPY-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H23F2N3O3S/c1-33(31,32)19-7-8-20(16-2-4-17(25)5-3-16)21(15-19)24(30)29-12-10-28(11-13-29)23-9-6-18(27)14-22(23)26/h2-9,14-15H,10-13,27H2,1H3
SMILES Code
O=C(N1CCN(C2=CC=C(N)C=C2F)CC1)C3=CC(S(=O)(C)=O)=CC=C3C4=CC=C(F)C=C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
Product Data
Biological target:
GSK575594A is a GPR55-selective agonist.
In vitro activity:
TBD
In vivo activity:
TBD

Preparing Stock Solutions

The following data is based on the product molecular weight 471.52 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Formulation protocol:
TBD
In vitro protocol:
TBD
In vivo protocol:
TBD
1: Brown AJ, Daniels DA, Kassim M, Brown S, Haslam CP, Terrell VR, Brown J, Nichols PL, Staton PC, Wise A, Dowell SJ. Pharmacology of GPR55 in yeast and identification of GSK494581A as a mixed-activity glycine transporter subtype 1 inhibitor and GPR55 agonist. J Pharmacol Exp Ther. 2011 Apr;337(1):236-46. doi: 10.1124/jpet.110.172650. PubMed PMID: 21233197.