Becocalcidiol | QRX 101 | DP-006 | COL-121 | CAS#524067-21-8 | vitamin D analog

MedKoo Cat#: 529308 | Name: Becocalcidiol

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Becocalcidiol, also known as QRX-101, DP-006 and COL-121, is a vitamin D analog potentially for the treatment of psoriasis.

Chemical Structure

Becocalcidiol

CAS#524067-21-8

Theoretical Analysis

MedKoo Cat#: 529308

Name: Becocalcidiol

CAS#: 524067-21-8

Chemical Formula: C23H36O2

Exact Mass: 344.2715

Molecular Weight: 344.53

Elemental Analysis: C, 80.18; H, 10.53; O, 9.29

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

QRX-101; DP-006; COL-121; QRX101; DP006; COL121; QRX 101; DP 006; COL 121; Becocalcidiol

IUPAC/Chemical Name

(1R,3R,E)-4-(2-((1R,3aS,7aR,E)-1-((S)-sec-butyl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)-2-methylenecyclohexane-1,3-diol

InChi Key

LIPXYRRLVFIGDM-GKBMBEDOSA-N

InChi Code

InChI=1S/C23H36O2/c1-5-15(2)19-11-12-20-17(7-6-14-23(19,20)4)8-9-18-10-13-21(24)16(3)22(18)25/h8-9,15,19-22,24-25H,3,5-7,10-14H2,1-2,4H3/b17-8+,18-9+/t15-,19+,20-,21+,22-,23+/m0/s1

SMILES Code

O[C@H]1C([C@H](O)/C(CC1)=C/C=C2[C@]3([H])CC[C@H]([C@H](CC)C)[C@@]3(C)CCC/2)=C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 344.53 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Helfrich YR, Kang S, Hamilton TA, Voorhees JJ. Topical becocalcidiol for the treatment of psoriasis vulgaris: a randomized, placebo-controlled, double-blind, multicentre study. Br J Dermatol. 2007 Aug;157(2):369-74. PubMed PMID: 17596167. 2: Mason AR, Mason J, Cork M, Dooley G, Hancock H. Topical treatments for chronic plaque psoriasis. Cochrane Database Syst Rev. 2013 Mar 28;(3):CD005028. doi: 10.1002/14651858.CD005028.pub3. Review. PubMed PMID: 23543539. 3: Bayés M, Rabasseda X. Gateways to clinical trials. Methods Find Exp Clin Pharmacol. 2008 Jan-Feb;30(1):67-99. PubMed PMID: 18389098.