GSK-264220A is an endothelial lipase and lipoprotein lipase inhibitor (IC50 values are 0.13 and 0.10 μM respectively).
MedKoo Cat#: 531881
Name: GSK-264220A
CAS#: 685506-42-7
Chemical Formula: C17H21N3O4S
Exact Mass: 363.1253
Molecular Weight: 363.43
Elemental Analysis: C, 56.18; H, 5.82; N, 11.56; O, 17.61; S, 8.82
| Solvent | mg/mL | mM | |
|---|---|---|---|
| Solubility | |||
| DMF | 30.0 | 82.55 | |
| DMSO | 33.2 | 91.27 | |
| DMSO:PBS (pH 7.2) (1:3) | 0.3 | 0.69 | |
| Ethanol | 2.1 | 5.68 |
The following data is based on the product molecular weight 363.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
