MedKoo Cat#: 531861 | Name: GR 89696 fumarate
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

GR 89696 fumarate is a highly potent and selective κ-opioid agonist (IC50 = 0.04 nM) that may be selective for the putative κ2 receptor. It is anti-nociceptive and neuroprotective in vivo.

Chemical Structure

GR 89696 fumarate
GR 89696 fumarate
CAS#126766-32-3

Theoretical Analysis

MedKoo Cat#: 531861

Name: GR 89696 fumarate

CAS#: 126766-32-3

Chemical Formula: C23H29Cl2N3O7

Exact Mass: 0.0000

Molecular Weight: 530.40

Elemental Analysis: C, 52.08; H, 5.51; Cl, 13.37; N, 7.92; O, 21.11

Price and Availability

Size Price Availability Quantity
10mg USD 450.00 2 Weeks
25mg USD 850.00 2 Weeks
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Related CAS #
126766-32-3 (fumarate); 126766-31-2 (free base).
Synonym
GR 89696 fumarate; GR 89696 (fumarate); GR 89696; GR89696; GR-89696.
IUPAC/Chemical Name
4-[(3,4-Dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid methyl ester fumarate
InChi Key
ABTNETSDXZBJTE-WLHGVMLRSA-N
InChi Code
InChI=1S/C19H25Cl2N3O3.C4H4O4/c1-27-19(26)23-8-9-24(15(13-23)12-22-6-2-3-7-22)18(25)11-14-4-5-16(20)17(21)10-14;5-3(6)1-2-4(7)8/h4-5,10,15H,2-3,6-9,11-13H2,1H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
SMILES Code
O=C(N1CC(CN2CCCC2)N(C(CC3=CC=C(Cl)C(Cl)=C3)=O)CC1)OC.O=C(O)/C=C/C(O)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 530.40 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Barber A, Bender HM, Gottschlich R, Greiner HE, Harting J, Mauler F, Seyfried CA. Effects of GR-89696 and the novel peripherally selective OP2 agonists, EMD-61569 and EMD-61747, against focal cerebral ischemia in the rat. Methods Find Exp Clin Pharmacol. 1999 Mar;21(2):105-13. PubMed PMID: 10327391.