MedKoo Cat#: 558288 | Name: Valibose

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Valibose An α-glucosidase inhibitor potentially for the treatment of diabetes. Valibose significantly decreased postprandial and fasting blood glucose, urine glucose, and reduced the levels of serum fructosamine. Valibose also decreased plasma triglyceride and cholesterol levels. Valibose ameliorated metabolic disturbance of glucose and lipids. In addition, valibose markedly reduced level of serum NAG and BUN, and decreased the weight index of kidney.

Chemical Structure

Valibose
Valibose
CAS#83470-79-5

Theoretical Analysis

MedKoo Cat#: 558288

Name: Valibose

CAS#: 83470-79-5

Chemical Formula: C10H21NO6

Exact Mass: 251.1369

Molecular Weight: 251.28

Elemental Analysis: C, 47.80; H, 8.42; N, 5.57; O, 38.20

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Valibose
IUPAC/Chemical Name
(1R,2S,3S,4S,6R)-4-((1,3-dihydroxypropan-2-yl)amino)-6-(hydroxymethyl)cyclohexane-1,2,3-triol
InChi Key
LWJUMCBIHCZWBT-JTBFQXKRSA-N
InChi Code
InChI=1S/C10H21NO6/c12-2-5-1-7(11-6(3-13)4-14)9(16)10(17)8(5)15/h5-17H,1-4H2/t5-,7+,8-,9+,10+/m1/s1
SMILES Code
O[C@H]1[C@@H](NC(CO)CO)C[C@H](CO)[C@@H](O)[C@@H]1O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 251.28 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Liu Q, Liu SN, Sun SJ, Shen ZF. [Valibose, an alpha-glucosidase inhibitor, ameliorates the metabolic disorder of glucose and lipids and the nephropathy in streptozotocin-induced diabetic rats]. Yao Xue Xue Bao. 2013 Aug;48(8):1227-32. Chinese. PubMed PMID: 24187828. 2: Zhong S, Zhong D, Chen X. Improved and simplified liquid chromatography/electrospray ionization mass spectrometry method for the analysis of underivatized glucosamine in human plasma. J Chromatogr B Analyt Technol Biomed Life Sci. 2007 Jul 1;854(1-2):291-8. PubMed PMID: 17544344. 3: Dai XM, An N, Wu JM, Li HY, Zhang QM. Development and validation of HPLC-UV-MS method for the control of four anti-diabetic drugs in suspected counterfeit products. Yao Xue Xue Bao. 2010 Mar;45(3):347-52. PubMed PMID: 21348424.