MedKoo Cat#: 513696 | Name: CID2440433
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

CID2440433, also known as ML-184, is a potent synthetic agonist of GPR55 (EC50 = 0.26 µM). GPR55 is a G protein-coupled receptor that is weakly activated by some cannabinoids (CBs) at nM concentrations but displays a 5- to 10-fold greater stimulation in response to 1 µM lysophosphatidylinositol (LPI).

Chemical Structure

CID2440433
CID2440433
CAS# 794572-10-4

Theoretical Analysis

MedKoo Cat#: 513696

Name: CID2440433

CAS#: 794572-10-4

Chemical Formula: C25H34N4O3S

Exact Mass: 470.2352

Molecular Weight: 470.63

Elemental Analysis: C, 63.80; H, 7.28; N, 11.90; O, 10.20; S, 6.81

Price and Availability

Size Price Availability Quantity
10mg USD 550.00 2 Weeks
50mg USD 1,250.00 2 Weeks
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Related CAS #
No Data
Synonym
CID2440433; CID-2440433; CID 2440433; ML-184; ML184; ML 184;
IUPAC/Chemical Name
3-[4-(2,3-dimethylphenyl)piperazine-1-carbonyl]-N,N-dimethyl-4-pyrrolidin-1-ylbenzenesulfonamide
InChi Key
VRSJAHQGJHDACS-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H34N4O3S/c1-19-8-7-9-23(20(19)2)28-14-16-29(17-15-28)25(30)22-18-21(33(31,32)26(3)4)10-11-24(22)27-12-5-6-13-27/h7-11,18H,5-6,12-17H2,1-4H3
SMILES Code
O=S(C1=CC=C(N2CCCC2)C(C(N3CCN(C4=CC=CC(C)=C4C)CC3)=O)=C1)(N(C)C)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 470.63 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Kotsikorou E, Madrigal KE, Hurst DP, Sharir H, Lynch DL, Heynen-Genel S, Milan LB, Chung TD, Seltzman HH, Bai Y, Caron MG, Barak L, Abood ME, Reggio PH. Identification of the GPR55 agonist binding site using a novel set of high-potency GPR55 selective ligands. Biochemistry. 2011 Jun 28;50(25):5633-47. doi: 10.1021/bi200010k. PubMed PMID: 21534610; PubMed Central PMCID: PMC3723401.