Vertilmicin Sulfate | CAS#857468-21-4 | Aminoglycoside Antibiotic

MedKoo Cat#: 527516 | Name: Vertilmicin Sulfate

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Vertilmicin Sulfate is an aminoglycoside antibiotic potentially for the treatment of bacterial infections.

Chemical Structure

Vertilmicin Sulfate

CAS#857468-21-4

Theoretical Analysis

MedKoo Cat#: 527516

Name: Vertilmicin Sulfate

CAS#: 857468-21-4

Chemical Formula: C44H96N10O34S5

Exact Mass:

Molecular Weight: 1469.59

Elemental Analysis: C, 35.96; H, 6.58; N, 9.53; O, 37.01; S, 10.91

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

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Synonym

Vertilmicin Sulfate; vertilmicin

IUPAC/Chemical Name

bis((2R,3R,4R,5R)-2-(((1S,2S,3R,4S,6R)-4-amino-3-(((2S,3R)-3-amino-6-(1-aminoethyl)-3,4-dihydro-2H-pyran-2-yl)oxy)-6-(ethylamino)-2-hydroxycyclohexyl)oxy)-5-methyl-4-(methylamino)tetrahydro-2H-pyran-3,5-diol) pentakis(sulfate)

InChi Key

YUZKIPGPNSUMPH-LNIIJANASA-N

InChi Code

InChI=1S/2C22H43N5O7.5H2O4S/c2*1-5-27-13-8-12(25)17(33-20-11(24)6-7-14(32-20)10(2)23)15(28)18(13)34-21-16(29)19(26-4)22(3,30)9-31-21;5*1-5(2,3)4/h2*7,10-13,15-21,26-30H,5-6,8-9,23-25H2,1-4H3;5*(H2,1,2,3,4)/t2*10?,11-,12+,13-,15+,16-,17-,18+,19-,20-,21-,22+;;;;;/m11...../s1

SMILES Code

O[C@H]([C@@H](NC)[C@@](CO1)(C)O)[C@H]1O[C@@H]2[C@@H](O)[C@H](O[C@@H]3[C@H](N)CC=C(C(N)C)O3)[C@@H](N)C[C@H]2NCC.O[C@H]([C@@H](NC)[C@@](CO4)(C)O)[C@H]4O[C@@H]5[C@@H](O)[C@H](O[C@@H]6[C@H](N)CC=C(C(N)C)O6)[C@@H](N)C[C@H]5NCC.O=S(O)(O)=O.O=S(O)(O)=O.O=S(O)(O)=O.O=S(O)(O)=O.O=S(O)(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 1,469.59 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Yuan YZ, Zhang M, Fan XL, Hu CQ, Jin SH, Van Schepdael A, Hoogmartens J, Adams E. Analysis of impurities in vertilmicin sulfate by liquid chromatography ion-trap mass spectrometry. J Pharm Biomed Anal. 2013 Jun;80:1-8. doi: 10.1016/j.jpba.2013.02.026. PubMed PMID: 23518304. 2: Wang J, Wang D, He H, Ni K. Determination of vertilmicin sulfate and its related substances by HPLC-ELSD and HPLC-MS2. J Chromatogr Sci. 2006 Oct;44(9):529-34. PubMed PMID: 17059677. 3: Liu Z, Duan G. Stability indicating reversed-phase ion-pairing liquid chromatographic determination of vertilmicin sulfate as bulk drug and in injections. J Pharm Biomed Anal. 2005 Mar 9;37(3):577-83. PubMed PMID: 15740919. 4: Huang TM, Deng CH, Chen NZ, Liu Z, Duan GL. High performance liquid chromatography for the determination of glucosamine sulfate in human plasma after derivatization with 9-fluorenylmethyl chloroformate. J Sep Sci. 2006 Oct;29(15):2296-302. PubMed PMID: 17120813.