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MedKoo Cat#: 513668 | Name: CGP13501

Description:

WARNING: This product is for research use only, not for human or veterinary use.

CGP 13501 is a positive allosteric modulator of GABAB receptor. In cells expressing GABAB(1b+2) receptors, CGP13501 increased GTPγ[35S] binding at Gαi1/3.

Chemical Structure

CGP13501
CGP13501
CAS#56189-68-5

Theoretical Analysis

MedKoo Cat#: 513668

Name: CGP13501

CAS#: 56189-68-5

Chemical Formula: C19H30O2

Exact Mass: 290.2246

Molecular Weight: 290.45

Elemental Analysis: C, 78.57; H, 10.41; O, 11.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
CGP13501; CGP 13501; CGP-13501.
IUPAC/Chemical Name
3-(3,5-ditert-butyl-4-hydroxyphenyl)-2,2-dimethylpropanal
InChi Key
XGWATTXMMMANFJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H30O2/c1-17(2,3)14-9-13(11-19(7,8)12-20)10-15(16(14)21)18(4,5)6/h9-10,12,21H,11H2,1-8H3
SMILES Code
O=CC(C)(C)CC1=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 290.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Mannoury la Cour C, Herbelles C, Pasteau V, de Nanteuil G, Millan MJ. Influence of positive allosteric modulators on GABA(B) receptor coupling in rat brain: a scintillation proximity assay characterisation of G protein subtypes. J Neurochem. 2008 Apr;105(2):308-23. PubMed PMID: 18021295. 2: Urwyler S, Mosbacher J, Lingenhoehl K, Heid J, Hofstetter K, Froestl W, Bettler B, Kaupmann K. Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol Pharmacol. 2001 Nov;60(5):963-71. PubMed PMID: 11641424.