MedKoo Cat#: 531484 | Name: ASN06917370

Description:

WARNING: This product is for research use only, not for human or veterinary use.

ASN06917370 is a GPR17 receptor modulator. ASN06917370 can be used for neuroprotective and/or reparatory purposes, in cerebral, cardiac and renal ischaemia, in cerebral trauma, in chronic neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), and in demyelinating diseases such as multiple sclerosis.

Chemical Structure

ASN06917370
ASN06917370
CAS#837404-68-9

Theoretical Analysis

MedKoo Cat#: 531484

Name: ASN06917370

CAS#: 837404-68-9

Chemical Formula: C24H21ClF3N7O2

Exact Mass: 531.1397

Molecular Weight: 531.92

Elemental Analysis: C, 54.19; H, 3.98; Cl, 6.66; F, 10.71; N, 18.43; O, 6.02

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
ASN06917370; ASN-06917370; ASN 06917370.
IUPAC/Chemical Name
4-(3-(2-chlorobenzyl)-7-oxo-4,7-dihydro-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)-N-(4-(trifluoromethyl)phenyl)piperidine-1-carboxamide
InChi Key
SKWHAHNDWJREJG-UHFFFAOYSA-N
InChi Code
InChI=1S/C24H21ClF3N7O2/c25-18-4-2-1-3-15(18)13-35-21-19(32-33-35)22(36)31-20(30-21)14-9-11-34(12-10-14)23(37)29-17-7-5-16(6-8-17)24(26,27)28/h1-8,14H,9-13H2,(H,29,37)(H,30,31,36)
SMILES Code
O=C(N1CCC(C2=NC(C(N=NN3CC4=C(Cl)C=CC=C4)=C3N2)=O)CC1)NC5=CC=C(C(F)(F)F)C=C5
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info
GPR17, a novel P2Y-like receptor belonging to the superfamily of G-protein coupled receptors (GPCRs), was identified as a new promising therapeutic target for the manipulation of brain dysfunctions resulting from ischaemia, trauma, acute or chronic diseases characterised by dysfunction of myelin, the sheath surrounding the nerve extensions that allows the transmission of impulses.

Preparing Stock Solutions

The following data is based on the product molecular weight 531.92 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL