TDRL-551 is a potent and selective Replication Protein A (RPA) inhibitor. TDRL-551 showed synergy with Pt in tissue culture models of EOC and in vivo efficacy, as a single agent and in combination with platinum, in a NSCLC xenograft model.
MedKoo Cat#: 407358
Name: TDRL-551
CAS#: 1644626-43-6
Chemical Formula: C25H23ClIN3O4
Exact Mass: 591.0422
Molecular Weight: 591.83
Elemental Analysis: C, 50.74; H, 3.92; Cl, 5.99; I, 21.44; N, 7.10; O, 10.81
The following data is based on the product molecular weight 591.83 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
