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MedKoo Cat#: 526534 | Name: UK-9040

Description:

WARNING: This product is for research use only, not for human or veterinary use.

UK-9040 is a gastric secretory inhibitor.

Chemical Structure

UK-9040
UK-9040
CAS#47453-14-5

Theoretical Analysis

MedKoo Cat#: 526534

Name: UK-9040

CAS#: 47453-14-5

Chemical Formula: C23H31NS

Exact Mass: 353.2177

Molecular Weight: 353.57

Elemental Analysis: C, 78.13; H, 8.84; N, 3.96; S, 9.07

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
UK-9040, UK 9040, UK9040
IUPAC/Chemical Name
Pyrrolidine, 1-(4-(5-(2,2-dimethylpropyl)-2-thienyl)-4-phenyl-3-butenyl)-, (Z)-
InChi Key
HZZXGWBOCXDVLV-MTJSOVHGSA-N
InChi Code
InChI=1S/C23H31NS/c1-23(2,3)18-20-13-14-22(25-20)21(19-10-5-4-6-11-19)12-9-17-24-15-7-8-16-24/h4-6,10-14H,7-9,15-18H2,1-3H3/b21-12-
SMILES Code
CC(C)(C)CC1=CC=C(/C(C2=CC=CC=C2)=C\CCN3CCCC3)S1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 353.57 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Hamer DB, Price AB, Baron JH. Morphological and pharmacological studies of the parietal cells of the stomach in the dog during periods of maximal acid output and after the gastric secretory inhibitor UK-9040. Gut. 1977 Feb;18(2):91-8. PubMed PMID: 852749; PubMed Central PMCID: PMC1411295. 2: Joffe SN, Polak JM, Pallone F, Bloom SR, Gaskin RJ, Barros D'sa AA, Baron JH. Gastrin, antral g cells, and gastric acid in secretagogue-induced and antihistamine-inhibited duodenal ulcers. Scand J Gastroenterol. 1977;12(1):27-32. PubMed PMID: 13481. 3: Joffe SN, Gaskin RJ, D'Sa AA. Prevention of secretagogue-induced ulcers in the rat. Gastroenterology. 1976 May;70(5 PT.1):751-2. PubMed PMID: 1261768. 4: Joffe SN, Gaskin R, Barros D'sa AA, Melo AA, Gribble JN, Girvan DP, Baron JH. Proceedings: Secretagogue-produced duodenal ulcers in the rat and their prevention by the gastric secretory inhibitor UK 9040. Br J Surg. 1975 Feb;62(2):157. PubMed PMID: 234768. 5: Hamer DB, Price AB, Baron JH. Proceedings: A morphological and pharmacological study of the parietal cells of the stomach in the dog during periods of maximal acid output and after the gastric secretory inhibitor UK-9040. Gut. 1974 Apr;15(4):336-7. PubMed PMID: 4151863. 6: Hamer DB, Baron JH, Spencer J. Studies with a new gastric secretory inhibitor (UK 9040) in the dog. Br J Surg. 1972 Nov;59(11):902. PubMed PMID: 4637105.