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MedKoo Cat#: 526469 | Name: Tolycaine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tolycaine is a local anaesthetic.

Chemical Structure

Tolycaine
CAS#3686-58-6

Theoretical Analysis

MedKoo Cat#: 526469

Name: Tolycaine

CAS#: 3686-58-6

Chemical Formula: C15H22N2O3

Exact Mass: 278.1630

Molecular Weight: 278.35

Elemental Analysis: C, 64.73; H, 7.97; N, 10.06; O, 17.24

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Tolycaine
IUPAC/Chemical Name
Methyl 2-(2-(diethylamino)acetamido)-m-toluate
InChi Key
UDKICLZCJWQTLS-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H22N2O3/c1-5-17(6-2)10-13(18)16-14-11(3)8-7-9-12(14)15(19)20-4/h7-9H,5-6,10H2,1-4H3,(H,16,18)
SMILES Code
CC1=C(NC(CN(CC)CC)=O)C(C(OC)=O)=CC=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 278.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Strugala GJ, Elsenhans B, Forth W. Active transport inhibition in rat small intestine by amphiphilic amines: an in vitro study with various local anaesthetics. Biochem Pharmacol. 2000 Apr 15;59(8):907-13. PubMed PMID: 10692555. 2: Satoh T, Sawaki K, Kawaguchi M. Pharmacological analysis of local anaesthetic tolycaine-induced convulsions by modification of monoamines in rat brain. Pharmacol Toxicol. 1996 Dec;79(6):305-11. PubMed PMID: 9000257. 3: Yoshii H. [Vasoconstrictor contained in local anesthetic--its effect on body temperature and circulatory kinetics]. Nichidai Koko Kagaku. 1989 Sep;15(3):216-38. Japanese. PubMed PMID: 2489796. 4: de Freitas JF. A rapid spectrophotometric assay of amide type dental anaesthetic agents. Aust Dent J. 1977 Jun;22(3):182-9. PubMed PMID: 270977.

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