HMR-1426 is gastric emptying inhibitor potentially for the treatment of obesity. In one study, HMR1426 showed an anorectic potential in rats and decreased body weight and fat mass. This was achieved solely by reducing food intake without influencing overall energy expenditure or behavior suggesting a peripheral mode of action. Thus, HMR1426 can be considered a potential new drug for obesity treatment.
MedKoo Cat#: 530140
Name: HMR-1426
CAS#: 262376-75-0
Chemical Formula: C16H12ClNOS
Exact Mass: 301.0300
Molecular Weight: 301.79
Elemental Analysis: C, 63.68; H, 4.01; Cl, 11.75; N, 4.64; O, 5.30; S, 10.62
The following data is based on the product molecular weight 301.79 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
