MedKoo Cat#: 530447 | Name: Tenovin-3
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tenovin-3 is a sirtuin inhibitor.

Chemical Structure

Tenovin-3
Tenovin-3
CAS#1011301-27-1

Theoretical Analysis

MedKoo Cat#: 530447

Name: Tenovin-3

CAS#: 1011301-27-1

Chemical Formula: C18H21N3OS

Exact Mass: 327.1405

Molecular Weight: 327.45

Elemental Analysis: C, 66.03; H, 6.46; N, 12.83; O, 4.89; S, 9.79

Price and Availability

Size Price Availability Quantity
10mg USD 250.00 2 Weeks
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
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Related CAS #
No Data
Synonym
Tenovin-3; Tenovin 3; Tenovin3.
IUPAC/Chemical Name
N-((4-aminophenyl)carbamothioyl)-4-(tert-butyl)benzamide
InChi Key
NLAXTZPUTNGRDU-UHFFFAOYSA-N
InChi Code
InChI=1S/C18H21N3OS/c1-18(2,3)13-6-4-12(5-7-13)16(22)21-17(23)20-15-10-8-14(19)9-11-15/h4-11H,19H2,1-3H3,(H2,20,21,22,23)
SMILES Code
CC(C)(C)C1=CC=C(C(NC(NC2=CC=C(N)C=C2)=S)=O)C=C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 327.45 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
Lv S, Pan Q, Lu W, Zhang W, Wang N, Huang L, Li L, Liu J, Ma J, Li Z, Huang Y, Deng Q, Lei X. Tenovin 3 induces apoptosis and ferroptosis in EGFR 19del non small cell lung cancer cells. Sci Rep. 2024 Apr 1;14(1):7654. doi: 10.1038/s41598-024-58499-5. Erratum in: Sci Rep. 2024 Jul 24;14(1):17087. doi: 10.1038/s41598-024-68087-2. PMID: 38561419; PMCID: PMC10985106.