SU 5214 | CAS#186611-04-1 | tyrosine kinase modulator

MedKoo Cat#: 531311 | Name: SU 5214

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SU 5214 is a modulator of tyrosine kinase signal transduction.

Chemical Structure

SU 5214

CAS#186611-04-1

Theoretical Analysis

MedKoo Cat#: 531311

Name: SU 5214

CAS#: 186611-04-1

Chemical Formula: C16H13NO2

Exact Mass: 251.0946

Molecular Weight: 251.29

Elemental Analysis: C, 76.48; H, 5.21; N, 5.57; O, 12.73

Price and Availability

Size	Price	Availability
1g	USD 2,450.00	2 Weeks
2g	USD 3,850.00	2 Weeks
5g	USD 5,750.00	2 Weeks

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Related CAS #

No Data

Synonym

SU 5214; SU-5214; SU5214

IUPAC/Chemical Name

3-(2-Methoxy-benzylidene)-1,3-dihydro-indol-2-one

InChi Key

NEQZEVOPIKSAJP-RAXLEYEMSA-N

InChi Code

InChI=1S/C16H13NO2/c1-19-15-9-5-2-6-11(15)10-13-12-7-3-4-8-14(12)17-16(13)18/h2-10H,1H3,(H,17,18)/b13-10-

SMILES Code

O=C1NC2=C(C=CC=C2)/C1=C/C3=CC=CC=C3OC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

To be determined

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Product Data

Product Data

Instruction

View handling instruction

Biological target:

SU 5214 has IC50s of 14.8 µM (FLK-1) and 36.7 µM (EGFR), respectively.

In vitro activity:

To be determined

In vivo activity:

To be determined

Preparing Stock Solutions

The following data is based on the product molecular weight 251.29 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

Formulation protocol:

To be determined

In vitro protocol:

To be determined

In vivo protocol:

To be determined

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