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MedKoo Cat#: 530224 | Name: SLV-310

Description:

WARNING: This product is for research use only, not for human or veterinary use.

SLV-310 is a novel, potential antipsychotic, combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition and 5-HT reuptake receptor inhibition. It has potential for treating a broad range of symptoms in schizophrenia.

Chemical Structure

SLV-310
SLV-310
CAS#264869-71-8

Theoretical Analysis

MedKoo Cat#: 530224

Name: SLV-310

CAS#: 264869-71-8

Chemical Formula: C25H24FN3O2

Exact Mass: 417.1853

Molecular Weight: 417.48

Elemental Analysis: C, 71.92; H, 5.79; F, 4.55; N, 10.07; O, 7.66

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
SLV-310; SLV 310; SLV-310; SLV310
IUPAC/Chemical Name
2-(4-(4-(5-fluoro-1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl)butyl)isoindoline-1,3-dione
InChi Key
NECJNLXOJRDELU-UHFFFAOYSA-N
InChi Code
InChI=1S/C25H24FN3O2/c26-18-7-8-23-21(15-18)22(16-27-23)17-9-13-28(14-10-17)11-3-4-12-29-24(30)19-5-1-2-6-20(19)25(29)31/h1-2,5-9,15-16,27H,3-4,10-14H2
SMILES Code
O=C1N(CCCCN2CC=C(C3=CNC4=C3C=C(F)C=C4)CC2)C(C5=C1C=CC=C5)=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 417.48 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: van Hes R, Smid P, Stroomer CN, Tipker K, Tulp MT, van der Heyden JA, McCreary AC, Hesselink MB, Kruse CG. SLV310, a novel, potential antipsychotic, combining potent dopamine D2 receptor antagonism with serotonin reuptake inhibition. Bioorg Med Chem Lett. 2003 Feb 10;13(3):405-8. PubMed PMID: 12565939. 2: Lange JH, Reinders JH, Tolboom JT, Glennon JC, Coolen HK, Kruse CG. Principal component analysis differentiates the receptor binding profiles of three antipsychotic drug candidates from current antipsychotic drugs. J Med Chem. 2007 Oct 18;50(21):5103-8. PubMed PMID: 17880057. 3: Jones CA, McCreary AC. Serotonergic approaches in the development of novel antipsychotics. Neuropharmacology. 2008 Nov;55(6):1056-65. doi: 10.1016/j.neuropharm.2008.05.025. Review. PubMed PMID: 18621404.