MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search
MedKoo Cat#: 531140 | Name: Fluensulfone
Featured New

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes.

Chemical Structure

Fluensulfone
Fluensulfone
CAS#318290-98-1

Theoretical Analysis

MedKoo Cat#: 531140

Name: Fluensulfone

CAS#: 318290-98-1

Chemical Formula: C7H5ClF3NO2S2

Exact Mass: 290.9402

Molecular Weight: 291.69

Elemental Analysis: C, 28.82; H, 1.73; Cl, 12.15; F, 19.54; N, 4.80; O, 10.97; S, 21.98

Price and Availability

Size Price Availability Quantity
25mg USD 450.00 2 Weeks
50mg USD 750.00 2 Weeks
100mg USD 1,250.00 2 Weeks
1g USD 4,250.00 2 Weeks
Bulk Inquiry
Buy Now
Add to Cart
Related CAS #
No Data
Synonym
Fluensulfone; MCW-2; MCW 2; MCW2
IUPAC/Chemical Name
5-chloro-2-(3,4,4-trifluorobut-3-ene-1-sulfonyl)-1,3-thiazole
InChi Key
XSNMWAPKHUGZGQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C7H5ClF3NO2S2/c8-5-3-12-7(15-5)16(13,14)2-1-4(9)6(10)11/h3H,1-2H2
SMILES Code
O=S(CC/C(F)=C(F)\F)(C1=NC=C(Cl)S1)=O
Appearance
Yellow to brown oil
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 291.69 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Grabau ZJ, Noling JW, Navia Gine PA. Fluensulfone and 1,3-dichloroprene for plant-parasitic nematode management in potato production. J Nematol. 2019;51:1-12. doi: 10.21307/jofnem-2019-038. PMID: 31339250; PMCID: PMC6916143. 2: Morris KA, Li X, Langston DB, Davis RF, Timper P, Grey TL. Fluensulfone sorption and mobility as affected by soil type. Pest Manag Sci. 2018 Feb;74(2):430-437. doi: 10.1002/ps.4724. Epub 2017 Oct 18. PMID: 28869328. 3: Oka Y. Sensitivity to fluensulfone of inactivated Meloidogyne spp. second- stage juveniles. Pest Manag Sci. 2020 Jul;76(7):2379-2387. doi: 10.1002/ps.5774. Epub 2020 Feb 18. PMID: 32027087. 4: Kearn J, Ludlow E, Dillon J, O'Connor V, Holden-Dye L. Fluensulfone is a nematicide with a mode of action distinct from anticholinesterases and macrocyclic lactones. Pestic Biochem Physiol. 2014 Feb;109:44-57. doi: 10.1016/j.pestbp.2014.01.004. Epub 2014 Jan 31. PMID: 24581383. 5: Hada A, Singh D, Venkata Satyanarayana KKV, Chatterjee M, Phani V, Rao U. Effect of fluensulfone on different functional genes of root-knot nematode Meloidogyne incognita. J Nematol. 2021 Aug 17;53:e2021-73. doi: 10.21307/jofnem-2021-073. PMID: 34414375; PMCID: PMC8371937. 6: Ploeg A, Stoddard S, Becker JO. Control of Meloidogyne incognita in sweetpotato with fluensulfone. J Nematol. 2019;51:1-8. doi: 10.21307/jofnem-2019-018. PMID: 31088030; PMCID: PMC6929636. 7: Shirley AM, Noe JP, Nyczepir AP, Brannen PM, Shirley BJ, Jagdale GB. Effect of spirotetramat and fluensulfone on population densities of Mesocriconema xenoplax and Meloidogyne incognita on peach. J Nematol. 2019;51:1-10. doi: 10.21307/jofnem-2019-012. PMID: 31088024; PMCID: PMC6929638. 8: Morris KA, Langston DB, Dickson DW, Davis RF, Timper P, Noe JP. Efficacy of Fluensulfone in a Tomato-Cucumber Double Cropping System. J Nematol. 2015 Dec;47(4):310-5. PMID: 26941459; PMCID: PMC4755705. 9: Oka Y, Saroya Y. Effect of fluensulfone and fluopyram on the mobility and infection of second-stage juveniles of Meloidogyne incognita and M. javanica. Pest Manag Sci. 2019 Aug;75(8):2095-2106. doi: 10.1002/ps.5399. Epub 2019 Apr 5. PMID: 30843368. 10: Zhang JJ, Cao W, Xi P, Li L, Qiao S, Luo H, Zhang J, Liu X, Du N. S-Glycosylation of Fluensulfone in Tomatoes: An Important Way of Fluensulfone Metabolism. J Agric Food Chem. 2021 Nov 10;69(44):12974-12984. doi: 10.1021/acs.jafc.1c04725. Epub 2021 Nov 1. PMID: 34723494. 11: Oka Y. Nematicidal activity of fluensulfone against some migratory nematodes under laboratory conditions. Pest Manag Sci. 2014 Dec;70(12):1850-8. doi: 10.1002/ps.3730. Epub 2014 Feb 25. PMID: 24452922. 12: Grabau ZJ, Liu C, Navia Gine PA. Belonolaimus longicaudatus management using metam potassium and fluensulfone in potato. J Nematol. 2023 Jul 6;55(1):20230028. doi: 10.2478/jofnem-2023-0028. PMID: 37426724; PMCID: PMC10324121. 13: Morris KA, Langston DB, Davis RF, Noe JP, Dickson DW, Timper P. Efficacy of Various Application Methods of Fluensulfone for Managing Root-knot Nematodes in Vegetables. J Nematol. 2016 Jun;48(2):65-71. doi: 10.21307/jofnem-2017-010. PMID: 27418698; PMCID: PMC4930317. 14: Feist E, Kearn J, Gaihre Y, O'Connor V, Holden-Dye L. The distinct profiles of the inhibitory effects of fluensulfone, abamectin, aldicarb and fluopyram on Globodera pallida hatching. Pestic Biochem Physiol. 2020 May;165:104541. doi: 10.1016/j.pestbp.2020.02.007. Epub 2020 Feb 5. PMID: 32359561. 15: Norshie PM, Grove IG, Back MA. Field evaluation of the nematicide fluensulfone for control of the potato cyst nematode Globodera pallida. Pest Manag Sci. 2016 Oct;72(10):2001-7. doi: 10.1002/ps.4329. Epub 2016 Jul 4. PMID: 27241192; PMCID: PMC5129520. 16: Oka Y, Shuker S, Tkachi N. Influence of soil environments on nematicidal activity of fluensulfone against Meloidogyne javanica. Pest Manag Sci. 2013 Nov;69(11):1225-34. doi: 10.1002/ps.3487. Epub 2013 Mar 1. PMID: 23456999. 17: Oka Y, Shuker S, Tkachi N. Systemic nematicidal activity of fluensulfone against the root-knot nematode Meloidogyne incognita on pepper. Pest Manag Sci. 2012 Feb;68(2):268-75. doi: 10.1002/ps.2256. Epub 2011 Aug 12. PMID: 21842527. 18: Zuo W, Wu Z, Xiong H, Zhou H, Wang C, Li J. Simultaneous determination of the nematicide fluensulfone and its two major metabolites in soils by ultra-high performance liquid chromatography-tandem mass spectrometry. J Chromatogr A. 2023 Aug 2;1702:464096. doi: 10.1016/j.chroma.2023.464096. Epub 2023 May 23. PMID: 37245354. 19: Cao X, Yang H, Liu C, Zhang R, Maienfisch P, Xu X. Bioisosterism and Scaffold Hopping in Modern Nematicide Research. J Agric Food Chem. 2022 Sep 14;70(36):11042-11055. doi: 10.1021/acs.jafc.2c00785. Epub 2022 May 12. PMID: 35549340. 20: Strupp C, Bomann W, Cohen SM, Weber K. Relationship of Metabolism and Cell Proliferation to the Mode of Action of Fluensulfone-Induced Mouse Lung Tumors. II: Additional Mechanistic Studies. Toxicol Sci. 2016 Dec;154(2):296-308. doi: 10.1093/toxsci/kfw168. Epub 2016 Sep 7. PMID: 27605420.

View History

Fludarabine diphosphate

Fludarabine diphosphate