Acitazanolast, also known MTCC and WP-871, is an anti-allergic drug candidate. Aerosol WP871 (0.01 and 0.033%) to some extent inhibited the antigen-induced bronchoconstriction in a dose-dependent fashion, but high-dose WP871 (0.1%) inhalation itself produced a non-specific bronchoconstriction. Aerosol WP871 does not antagonize SRS-A, but inhibits synthesis and/or release of SRS-A and has some non-specific bronchoconstrictive effect in high concentration.
MedKoo Cat#: 329463
Name: Acitazanolast
CAS#: 114607-46-4
Chemical Formula: C9H7N5O3
Exact Mass: 233.0549
Molecular Weight: 233.19
Elemental Analysis: C, 46.36; H, 3.03; N, 30.03; O, 20.58
The following data is based on the product molecular weight 233.19 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
