Belaperidone, also known as LU-111995, is a novel antipsychotic drug in clinical development. It has a clozapine-like receptor profile and affinities for dopamine D(4) and 5-hydroxytryptamine(2A) receptors. LU111995 prolongs the Q-T interval to a limited degree and is not arrhythmogenic over the physiological range of CLs. LU-111995 exhibits potential antipsychotic-like activity in two models of disrupted PPI.
MedKoo Cat#: 329443
Name: Belaperidone
CAS#: 208661-17-0
Chemical Formula: C22H22FN3O2
Exact Mass: 379.1696
Molecular Weight: 379.44
Elemental Analysis: C, 69.64; H, 5.84; F, 5.01; N, 11.07; O, 8.43
The following data is based on the product molecular weight 379.44 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
