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MedKoo Cat#: 526340 | Name: Sisapronil

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sisapronil, also known as PF-0241851, is an ectoparasiticide and a member of the phenylpyrazole class of antiparasitics.

Chemical Structure

Sisapronil
Sisapronil
CAS#856225-89-3

Theoretical Analysis

MedKoo Cat#: 526340

Name: Sisapronil

CAS#: 856225-89-3

Chemical Formula: C15H6Cl2F8N4

Exact Mass: 463.9842

Molecular Weight: 465.13

Elemental Analysis: C, 38.73; H, 1.30; Cl, 15.24; F, 32.68; N, 12.05

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Sisapronil; PF-0241851; PF 0241851; PF0241851.
IUPAC/Chemical Name
1H-Pyrazole-3-carbonitrile, 5-amino-1-(2,6-dichloro-4-(trifluoromethyl)phenyl)-4-(2,2-difluoro-1-(trifluoromethyl)cyclopropyl)-
InChi Key
VBAVKJPWXSLDSG-UHFFFAOYSA-N
InChi Code
InChI=1S/C15H6Cl2F8N4/c16-6-1-5(14(20,21)22)2-7(17)10(6)29-11(27)9(8(3-26)28-29)12(15(23,24)25)4-13(12,18)19/h1-2H,4,27H2
SMILES Code
N#CC1=NN(C2=C(Cl)C=C(C(F)(F)F)C=C2Cl)C(N)=C1C3(C(F)(F)F)C(F)(F)C3
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 465.13 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: World Health Organization.. Evaluation of certain veterinary drug residues in food. Eighty-first report of the Joint FAO/WHO Expert Committee on Food Additives. World Health Organ Tech Rep Ser. 2016;(997):1-110. PubMed PMID: 27509597. 2: Riviere JE, Brooks JD, Collard WT, Deng J, de Rose G, Mahabir SP, Merritt DA, Marchiondo AA. Prediction of formulation effects on dermal absorption of topically applied ectoparasiticides dosed in vitro on canine and porcine skin using a mixture-adjusted quantitative structure permeability relationship. J Vet Pharmacol Ther. 2014 Oct;37(5):435-44. doi: 10.1111/jvp.12121. PubMed PMID: 24649911.