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MedKoo Cat#: 526317 | Name: Sch 44643

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sch 44643 is an orally active antagonist of platelet activating factor.

Chemical Structure

Sch 44643
Sch 44643
CAS#133330-43-5

Theoretical Analysis

MedKoo Cat#: 526317

Name: Sch 44643

CAS#: 133330-43-5

Chemical Formula: C25H23ClN3O2-

Exact Mass: 432.1484

Molecular Weight: 432.93

Elemental Analysis: C, 69.36; H, 5.36; Cl, 8.19; N, 9.71; O, 7.39

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Sch 44643; Sch44643; Sch-44643.
IUPAC/Chemical Name
4-(4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carbonyl)pyridin-1(2H)-olate
InChi Key
InChi Code
SMILES Code
[O-]N1C=CC(C(N2CC/C(CC2)=C3C4=CC=C(Cl)C=C4CCC5=CC=CN=C5\3)=O)=CC1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 432.93 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Lin CC, Billah M, Kim HK, Egan R, Anthes J, Gilchrest H, Cayen M. Determination of plasma concentrations of SCH 44643 by a GC method and correlation of plasma concentration and anti-PAF activity in cynomolgus monkeys. J Pharm Biomed Anal. 1996 Dec;15(3):343-7. PubMed PMID: 8951694.

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