Synonym
Sch 40120; Sch40120; Sch-40120.
IUPAC/Chemical Name
Benzo(b)(1,8)naphthyridin-5(7H)-one, 10-(3-chlorophenyl)-6,8,9,10-tetrahydro-
SMILES Code
O=C1C(CCCC2)=C2N(C3=CC=CC(Cl)=C3)C4=NC=CC=C14
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
Preparing Stock Solutions
The following data is based on the
product
molecular weight
310.78
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Wang CJ, Tian Z, Reyes V, Lin CC. A specific enzyme immunoassay (EIA) with selective extraction for quantitation of a topical anti-inflammatory agent, SCH 40120, in human plasma. J Pharm Biomed Anal. 1995 Feb;13(2):121-7. PubMed PMID: 7766718.
2: Wang CJ, Tian Z, Gommoll C, Reyes V, Lin CC. A sensitive enzyme immunoassay (EIA) for quantitation of the topical anti-inflammatory agent SCH 40120 in unextracted human plasma. J Pharm Biomed Anal. 1993 Oct;11(10):871-9. PubMed PMID: 8305589.
3: Smith SR, Watnick AS, Kung T, Siegel MI. In vitro and in vivo immunopharmacological profile of Sch 40120. Immunopharmacol Immunotoxicol. 1993 Jan;15(1):13-44. PubMed PMID: 8450179.
4: Smith SR, Watnick AW, Bryant RW, Billah M, Siegel MI. Actions of a 5-lipoxygenase inhibitor, Sch 40120, on acute inflammatory responses. J Pharmacol Exp Ther. 1992 Aug;262(2):721-8. PubMed PMID: 1386887.
