Sch 24937 | CAS#75696-17-2 | immunosuppressant

MedKoo Cat#: 526286 | Name: Sch 24937

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Sch 24937 is an immunosuppressant with potent inhibitory effects on B lymphocyte mediated immune responses.

Chemical Structure

Sch 24937

CAS#75696-17-2

Theoretical Analysis

MedKoo Cat#: 526286

Name: Sch 24937

CAS#: 75696-17-2

Chemical Formula: C16H12BrClN2O2S

Exact Mass: 409.9491

Molecular Weight: 411.70

Elemental Analysis: C, 46.68; H, 2.94; Br, 19.41; Cl, 8.61; N, 6.80; O, 7.77; S, 7.79

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

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Synonym

Sch 24937; Sch 24937; Sch 24937.

IUPAC/Chemical Name

6-Bromo-5-chloro-2-((methylsulfinyl)acetyl)-3-(2-pyridyl)indole

InChi Key

InChi Code

SMILES Code

O=C(C(N1)=C(C2=NC=CC=C2)C3=C1C=C(Br)C(Cl)=C3)CS(C)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

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Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 411.70 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Smith SR, Pennline KJ, Bober LA, Kenworthy-Bott L, Phillips L, Pellerito F, da Fonseca M, Terminelli C. Inhibition of collagen II-induced arthritis in mice--a comparison of the effects of Sch 24937, immunosuppressants and nonsteroidal antiinflammatory drugs on the clinical expression of disease. Int J Immunopharmacol. 1990;12(2):165-73. PubMed PMID: 2329010. 2: Smith SR, Terminelli C, Epps S, Watnick A, Umland S. A study of the immunosuppressive properties of Sch 24937. Immunopharmacol Immunotoxicol. 1987;9(2-3):333-59. PubMed PMID: 2963854.