NS-2710 | CAS#184220-36-8

MedKoo Cat#: 526948 | Name: NS-2710

Description:

WARNING: This product is for research use only, not for human or veterinary use.

NS-2710 is a GABA receptor agonist potentially for the treatment of anxiety.

Chemical Structure

NS-2710

CAS#184220-36-8

Theoretical Analysis

MedKoo Cat#: 526948

Name: NS-2710

CAS#: 184220-36-8

Chemical Formula: C22H20N4O

Exact Mass: 356.1637

Molecular Weight: 356.43

Elemental Analysis: C, 74.14; H, 5.66; N, 15.72; O, 4.49

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

NS-2710; NS 2710; NS2710.

IUPAC/Chemical Name

(E)-1-(1-(3-(pyridin-3-yl)phenyl)-1H-benzo[d]imidazol-5-yl)ethan-1-one O-ethyl oxime

InChi Key

NHJFEXZXSCFYRX-PCLIKHOPSA-N

InChi Code

InChI=1S/C22H20N4O/c1-3-27-25-16(2)17-9-10-22-21(13-17)24-15-26(22)20-8-4-6-18(12-20)19-7-5-11-23-14-19/h4-15H,3H2,1-2H3/b25-16+

SMILES Code

C/C(C1=CC=C2N(C3=CC=CC(C4=CC=CN=C4)=C3)C=NC2=C1)=N\OCC

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 356.43 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Atack JR. GABAA receptor subtype-selective modulators. I. α2/α3-selective agonists as non-sedating anxiolytics. Curr Top Med Chem. 2011;11(9):1176-202. Review. PubMed PMID: 21050172. 2: Evenden J, Duncan B, Ko T. A comparison of the effects of psychotomimetics and anxiolytics on punished and unpunished responding maintained by fixed interval schedules of food reinforcement in the rat. Behav Pharmacol. 2006 Feb;17(1):87-99. PubMed PMID: 16377966. 3: Mirza NR, Nielsen EØ. Do subtype-selective gamma-aminobutyric acid A receptor modulators have a reduced propensity to induce physical dependence in mice? J Pharmacol Exp Ther. 2006 Mar;316(3):1378-85. PubMed PMID: 16352707. 4: Atack JR. Anxioselective compounds acting at the GABA(A) receptor benzodiazepine binding site. Curr Drug Targets CNS Neurol Disord. 2003 Aug;2(4):213-32. Review. PubMed PMID: 12871032.