T-2000 | DMMDPB | CAS#97846-21-4 | GABA Receptor Agonist

MedKoo Cat#: 526946 | Name: T-2000

Description:

WARNING: This product is for research use only, not for human or veterinary use.

T-2000, also known as DMMDPB, is a GABA receptor agonist potentially for the treatment of essential tremor.

Chemical Structure

T-2000

CAS#97846-21-4

Theoretical Analysis

MedKoo Cat#: 526946

Name: T-2000

CAS#: 97846-21-4

Chemical Formula: C20H20N2O5

Exact Mass: 368.1372

Molecular Weight: 368.39

Elemental Analysis: C, 65.21; H, 5.47; N, 7.60; O, 21.71

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

T-2000, T 2000, T2000, DMMDPB

IUPAC/Chemical Name

1,3-Dimethoxymethyl-5,5-diphenylbarbituric acid

InChi Key

RRFBTKHQZRCRSS-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H20N2O5/c1-26-13-21-17(23)20(15-9-5-3-6-10-15,16-11-7-4-8-12-16)18(24)22(14-27-2)19(21)25/h3-12H,13-14H2,1-2H3

SMILES Code

O=C(N(COC)C(C1(C2=CC=CC=C2)C3=CC=CC=C3)=O)N(COC)C1=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 368.39 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Hadj Tahar A, Chuang R, Steeves T, Jog M, Lang A, Grimes D. Efficacy and safety of T2000 in older patients with essential tremor. Parkinsonism Relat Disord. 2013 Apr;19(4):485-6. doi: 10.1016/j.parkreldis.2012.11.014. PubMed PMID: 23254160. 2: Melmed C, Moros D, Rutman H. Treatment of essential tremor with the barbiturate T2000 (1,3-dimethoxymethyl-5,5-diphenyl-barbituric acid). Mov Disord. 2007 Apr 15;22(5):723-7. PubMed PMID: 17265458.