Ro 07-1902 | CAS#526136

MedKoo Cat#: 526136 | Name: Ro 07-1902

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ro 07-1902 enhances the effect of specific antineoplastic agents.

Chemical Structure

Ro 07-1902

CAS#526136

Theoretical Analysis

MedKoo Cat#: 526136

Name: Ro 07-1902

CAS#: 526136

Chemical Formula: C9H13N3O4

Exact Mass: 227.0906

Molecular Weight: 227.22

Elemental Analysis: C, 47.57; H, 5.77; N, 18.49; O, 28.16

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

Ro 07-1902; Ro-07-1902; Ro07-1902.

IUPAC/Chemical Name

2-Nitro-alpha-((1-propenyloxy)methyl)imidazole-1-ethanol

InChi Key

XVAVDAAXADYTPR-GORDUTHDSA-N

InChi Code

InChI=1S/C9H13N3O4/c1-2-5-16-7-8(13)6-11-4-3-10-9(11)12(14)15/h2-5,8,13H,6-7H2,1H3/b5-2+

SMILES Code

OC(CO/C=C/C)CN1C=CN=C1[N+]([O-])=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 227.22 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Lee FY, Workman P. Interaction of nitroimidazole sensitizers with drug metabolizing enzymes--spectral and kinetic studies. Int J Radiat Oncol Biol Phys. 1986 Aug;12(8):1383-7. PubMed PMID: 3759560. 2: Chaplin DJ, Sheldon PW, Ahmed I, Adams GE. Potentiation of cyclophosphamide cytotoxicity in vivo: a study with misonidazole and fifteen other 1-substituted 2-nitroimidazoles. Int J Radiat Oncol Biol Phys. 1984 Sep;10(9):1647-51. PubMed PMID: 6480452. 3: Lee FY, Workman P. Nitroimidazoles as modifiers of nitrosourea pharmacokinetics. Int J Radiat Oncol Biol Phys. 1984 Sep;10(9):1627-30. PubMed PMID: 6237080. 4: Twentyman PR, Workman P. Chemosensitization by lipophilic nitroimidazoles. Br J Cancer. 1983 Jul;48(1):17-26. PubMed PMID: 6871076; PubMed Central PMCID: PMC2011422. 5: Workman P, Twentyman PR. Structure/activity relationships for the enhancement by electron-affinic drugs of the anti-tumour effect of CCNU. Br J Cancer. 1982 Aug;46(2):249-59. PubMed PMID: 7150475; PubMed Central PMCID: PMC2011106. 6: Workman P, Twentyman PR. Enhancement by electron-affinic agents of the therapeutic effects of cytotoxic agents against the KHT tumor: structure-activity relationships. Int J Radiat Oncol Biol Phys. 1982 Mar-Apr;8(3-4):623-6. PubMed PMID: 7107385. 7: Twentyman PR, Workman P. The effect of radiosensitizer pretreatment on the response of the RIF-1 mouse sarcoma to cytotoxic drugs. Int J Radiat Oncol Biol Phys. 1982 Mar-Apr;8(3-4):611-3. PubMed PMID: 7107382.