SL-017, also known as ACP-SL-017; ACPSL-017; ACP-SL-017, is a Hypocrellin-B (HB) derivative and photosensitiser potentially for the treatment of hair growth abnormality. SL017 treatment resulted in increased mitochondrial fragmentation which followed loss of ΔΨm. SL017 targets mitochondria, triggering collapse of mitochondrial membrane potential, generates ROS and subsequently results in mitochondrial fragmentation.
MedKoo Cat#: 326964
Name: SL-017
CAS#: 1169831-01-9
Chemical Formula: C34H34N2O8
Exact Mass: 598.2315
Molecular Weight: 598.65
Elemental Analysis: C, 68.22; H, 5.72; N, 4.68; O, 21.38
The following data is based on the product molecular weight 598.65 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
