Tetridamine | POLI-67 | CAS#17289-49-5 | Analgesic & Anti-Inflammatory

MedKoo Cat#: 328304 | Name: Tetridamine

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Tetridamine, also known as POLI-67, is an analgesic and anti-inflammatory drug used to treat vaginitis.

Chemical Structure

Tetridamine

CAS#17289-49-5

Theoretical Analysis

MedKoo Cat#: 328304

Name: Tetridamine

CAS#: 17289-49-5

Chemical Formula: C9H15N3

Exact Mass: 165.1266

Molecular Weight: 165.24

Elemental Analysis: C, 65.42; H, 9.15; N, 25.43

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

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Related CAS #

No Data

Synonym

Tetridamine; POLI-67; POLI 67; POLI67

IUPAC/Chemical Name

N,2-dimethyl-4,5,6,7-tetrahydro-2H-indazol-3-amine

InChi Key

NKDJNEGDJVXHKM-UHFFFAOYSA-N

InChi Code

InChI=1S/C9H15N3/c1-10-9-7-5-3-4-6-8(7)11-12(9)2/h10H,3-6H2,1-2H3

SMILES Code

CNC1=C2CCCCC2=NN1C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 165.24 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Manzardo S, Girardello R, Pinzetta A, Coppi G, De Aloysio D. Activity and tolerability of tetridamine vaginal lavage in rats and women. Boll Chim Farm. 1992 Mar;131(3):113-6. PubMed PMID: 1418890. 2: Ballesterosé S, Ramón MF, Martínez-Arrieta R. Oral tetridamine exposures. Clin Toxicol (Phila). 2009 Feb;47(2):150-2. doi: 10.1080/15563650801938688. PubMed PMID: 18608303. 3: Pugliares S, Jacobellis M. [Tetridamine in the therapy of bacterial vaginosis]. Minerva Ginecol. 1991 May;43(5):245-51. Review. Italian. PubMed PMID: 1881569. 4: Massaroli G, Cellari C, Coerezza M, Scuri R. [Absorption, metabolism and excretion of 2-methyl-3-methylamino-4,5,6,7-tetrahydroindazole (tetridamine) in the rat]. Boll Chim Farm. 1972 Nov;111(11):649-57. Italian. PubMed PMID: 4655669.