PF-46396 is a HIV maturation inhibitor. PF-46396 displayed potent activity against HIV-1 clade B. PF-46396 as a broadly active maturation inhibitor can be used against HIV-1 clade B and C and help in rational designing of novel analogs with reduced toxicity and increased efficacy for its potential use in clinics.
MedKoo Cat#: 525932
Name: PF-46396
CAS#: 1207481-21-7
Chemical Formula: C27H29F3N2O
Exact Mass: 454.2232
Molecular Weight: 454.54
Elemental Analysis: C, 71.35; H, 6.43; F, 12.54; N, 6.16; O, 3.52
The following data is based on the product molecular weight 454.54 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
