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MedKoo Cat#: 525559 | Name: LY-127210 free base

Description:

WARNING: This product is for research use only, not for human or veterinary use.

LY-127210 free base is a novel antihypertensive agent. It is peripheral arterial vasodilator that reduces mean arterial blood.

Chemical Structure

LY-127210 free base
LY-127210 free base
CAS#57184-68-6

Theoretical Analysis

MedKoo Cat#: 525559

Name: LY-127210 free base

CAS#: 57184-68-6

Chemical Formula: C12H14N2O2

Exact Mass: 218.1055

Molecular Weight: 218.26

Elemental Analysis: C, 66.04; H, 6.47; N, 12.84; O, 14.66

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
LY-127210 free base; LY 127210; LY127210.
IUPAC/Chemical Name
1H-3-Benzazepin-2-amine, 7,8-dimethoxy-
InChi Key
WADYQLCXAVXCQZ-UHFFFAOYSA-N
InChi Code
InChI=1S/C12H14N2O2/c1-15-10-5-8-3-4-14-12(13)7-9(8)6-11(10)16-2/h3-6H,7H2,1-2H3,(H2,13,14)
SMILES Code
NC1=NC=CC2=CC(OC)=C(OC)C=C2C1
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 218.26 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Petersen BH, Heim MC, White JF. Experimental drug-induced immune thrombocytopenia in monkeys. Diagn Clin Immunol. 1988;5(6):349-54. PubMed PMID: 3064948. 2: Steinberg MI, Keller CE, Bemis KG. Hemodynamic and vascular activity of LY127210, a new vasodilator, in anesthetized spontaneously hypertensive rats: comparison with hydralazine. Clin Exp Hypertens A. 1985;7(10):1481-97. PubMed PMID: 3841035. 3: Ruffolo RR Jr, Kurz K, Paget CJ. Evaluation of a novel antihypertensive agent, LY127210, in anesthetized and conscious spontaneously hypertensive rats. J Pharmacol Exp Ther. 1985 Jan;232(1):134-8. PubMed PMID: 3838104.