Synonym
LY 150310; LY-150310; LY150310.
IUPAC/Chemical Name
1H-Imidazole, 1-(1,2,3,4-tetrahydro-1-naphthalenyl)-
InChi Key
RUKUDYPTXIUUKQ-UHFFFAOYSA-N
InChi Code
InChI=1S/C13H14N2/c1-2-6-12-11(4-1)5-3-7-13(12)15-9-8-14-10-15/h1-2,4,6,8-10,13H,3,5,7H2
SMILES Code
N1(C2CCCC3=C2C=CC=C3)C=CN=C1
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
Preparing Stock Solutions
The following data is based on the
product
molecular weight
198.26
Batch specific molecular weights may vary
from batch to batch
due to the degree of hydration, which will
affect the solvent
volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass |
1 mg |
5 mg |
10 mg |
| 1 mM |
1.15 mL |
5.76 mL |
11.51 mL |
| 5 mM |
0.23 mL |
1.15 mL |
2.3 mL |
| 10 mM |
0.12 mL |
0.58 mL |
1.15 mL |
| 50 mM |
0.02 mL |
0.12 mL |
0.23 mL |
1: Stengel PW, Dillard RD, Cho HL, Snyder DW, Spaethe SM, Pechous PA, Obenchain RL, Cockerham SL, Silbaugh SA. Bronchopulmonary actions of 1-(1,2,3,4-tetrahydro-1-naphthylenyl)-1H-imidazole, nitric acid salt (LY150310), a substituted imidazole, in the guinea pig. J Pharmacol Exp Ther. 1993 Nov;267(2):596-603. PubMed PMID: 8246133.
2: Merriman RL, Shackelford KA, Tanzer LR, Campbell JB, Bemis KG, Matsumoto K. Drug treatments for metastasis of the Lewis lung carcinoma: lack of correlation between inhibition of lung metastasis and survival. Cancer Res. 1989 Aug 15;49(16):4509-16. PubMed PMID: 2743339.
