PD 118717 | Dopamine Autoreceptor Agonist | CAS#104229-37-0

MedKoo Cat#: 525826 | Name: PD 118717

Description:

WARNING: This product is for research use only, not for human or veterinary use.

PD 118717 is a putative piperazinyl benzopyranone dopamine autoreceptor agonist.PD 118717 has the profile of a DA autoreceptor agonist in neurochemical and neurophysiological tests and produces effects suggestive of antipsychotic efficacy without neurological side effect liability in preclinical behavioral tests.

Chemical Structure

PD 118717

CAS#104229-37-0

Theoretical Analysis

MedKoo Cat#: 525826

Name: PD 118717

CAS#: 104229-37-0

Chemical Formula: C20H24N4O7S

Exact Mass: 464.1366

Molecular Weight: 464.49

Elemental Analysis: C, 51.72; H, 5.21; N, 12.06; O, 24.11; S, 6.90

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

PD118717; PD-118717; PD 118717

IUPAC/Chemical Name

7-(3-(4-(pyrimidin-2-yl)piperazin-1-yl)propoxy)-2H-chromen-2-one sulfate

InChi Key

YGJZQALBRCKWHA-UHFFFAOYSA-N

InChi Code

InChI=1S/C20H22N4O3.H2O4S/c25-19-6-4-16-3-5-17(15-18(16)27-19)26-14-2-9-23-10-12-24(13-11-23)20-21-7-1-8-22-20;1-5(2,3)4/h1,3-8,15H,2,9-14H2;(H2,1,2,3,4)

SMILES Code

O=C1C=CC2=CC=C(OCCCN3CCN(C4=NC=CC=N4)CC3)C=C2O1.O=S(O)(O)=O

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 464.49 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Pugsley TA, Christofferson CL, Corbin A, DeWald HA, Demattos S, Meltzer LT, Myers SL, Shih YH, Whetzel SZ, Wiley JN, et al. Pharmacological characterization of PD 118717, a putative piperazinyl benzopyranone dopamine autoreceptor agonist. J Pharmacol Exp Ther. 1992 Dec;263(3):1147-58. PubMed PMID: 1361570.