JNJ-42259152 is a novel phosphodiesterase 10A PET tracer. Kinetic modeling of (18)F-JNJ-42259152 shows that PDE10A activity can be reliably quantified and simplified using a reference tissue model with the frontal cortex as reference and a 60-min acquisition period.
MedKoo Cat#: 525407
Name: JNJ-42259152
CAS#: 1301167-87-2
Chemical Formula: C24H23FN4O
Exact Mass: 402.1856
Molecular Weight: 402.46
Elemental Analysis: C, 71.62; H, 5.76; F, 4.72; N, 13.92; O, 3.98
The following data is based on the product molecular weight 402.46 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
