Hoku 81 is a bronchodilator, and one of the metabolites of tulobuterol. HOKU-81 was approximately 8 times more potent than tulobuterol, approximately twice as potent as salbutamol, and approximately as potent as isoprenaline in relaxing effect on the isolated tracheal smooth muscle preparation of guinea pigs.
MedKoo Cat#: 526797
Name: Hoku 81
CAS#: 58020-43-2
Chemical Formula: C12H18ClNO2
Exact Mass: 243.1026
Molecular Weight: 243.73
Elemental Analysis: C, 59.14; H, 7.44; Cl, 14.54; N, 5.75; O, 13.13
The following data is based on the product molecular weight 243.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
