JNJ-26146900 is a nonsteroidal androgen receptor (AR) ligand with tissue-selective activity in rats. It binds to the rat AR with a K(i) of 400nM and acts as a pure androgen antagonist in an in vitro cell-based assay. JNJ-26146900 has the potential for anabolic effects on bone and muscle while maintaining therapeutic efficacy in prostate cancer.
MedKoo Cat#: 525316
Name: JNJ-26146900
CAS#: 868691-50-3
Chemical Formula: C15H15F3N2O3S
Exact Mass: 360.0756
Molecular Weight: 360.35
Elemental Analysis: C, 50.00; H, 4.20; F, 15.82; N, 7.77; O, 13.32; S, 8.90
The following data is based on the product molecular weight 360.35 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 1 mM | 1.15 mL | 5.76 mL | 11.51 mL |
| 5 mM | 0.23 mL | 1.15 mL | 2.3 mL |
| 10 mM | 0.12 mL | 0.58 mL | 1.15 mL |
| 50 mM | 0.02 mL | 0.12 mL | 0.23 mL |
