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MedKoo Cat#: 525802 | Name: Ono-RS 347

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Ono-RS 347 is an SRS-A antagonist. It is a new leukotriene antagonists.

Chemical Structure

Ono-RS 347
Ono-RS 347
CAS#103176-67-6

Theoretical Analysis

MedKoo Cat#: 525802

Name: Ono-RS 347

CAS#: 103176-67-6

Chemical Formula: C26H25N5O4

Exact Mass: 471.1907

Molecular Weight: 471.51

Elemental Analysis: C, 66.23; H, 5.34; N, 14.85; O, 13.57

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
Ono-RS-347; Ono RS-347; Ono RS 347; Ono-RS 347
IUPAC/Chemical Name
N-(3-(1H-tetrazol-5-yl)-2,3-dihydrobenzo[b][1,4]dioxin-5-yl)-4-(4-phenylbutoxy)benzamide
InChi Key
CILFBYXDVWMEGJ-UHFFFAOYSA-N
InChi Code
InChI=1S/C26H25N5O4/c32-26(19-12-14-20(15-13-19)33-16-5-4-9-18-7-2-1-3-8-18)27-21-10-6-11-22-24(21)35-23(17-34-22)25-28-30-31-29-25/h1-3,6-8,10-15,23H,4-5,9,16-17H2,(H,27,32)(H,28,29,30,31)
SMILES Code
O=C(NC1=C2OC(C3=NN=NN3)COC2=CC=C1)C4=CC=C(OCCCCC5=CC=CC=C5)C=C4
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 471.51 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Adaikan PG, Lau LC, Kottegoda SR, Ratnam SS. Effects of two new leukotriene antagonists ONO-RS-347 and ONO-RS-411 (ONO-1078) on the guinea pig and human respiratory and other systems. Adv Prostaglandin Thromboxane Leukot Res. 1987;17A:549-53. PubMed PMID: 2959112. 2: Obata T, Katsube N, Miyamoto T, Toda M, Okegawa T, Nakai H, Kosuge S, Konno M, Arai Y, Kawasaki A. New antagonists of leukotrienes: ONO-RS-411 and ONO-RS-347. Adv Prostaglandin Thromboxane Leukot Res. 1985;15:229-31. PubMed PMID: 2936099.

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Cy3B carboxylic acid

Cy3B carboxylic acid

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