MedKoo Cat#: 525256 | Name: Hoquizil hydrochloride

Description:

WARNING: This product is for research use only, not for human or veterinary use.

Hoquizil hydrochloride is a new oral bronchodilator.

Chemical Structure

Hoquizil hydrochloride
Hoquizil hydrochloride
CAS#23256-28-2

Theoretical Analysis

MedKoo Cat#: 525256

Name: Hoquizil hydrochloride

CAS#: 23256-28-2

Chemical Formula: C19H27ClN4O5

Exact Mass:

Molecular Weight: 426.89

Elemental Analysis: C, 53.46; H, 6.37; Cl, 8.30; N, 13.12; O, 18.74

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
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Synonym
Hoquizil hydrochloride; Hoquizil HCl; CP-14,185-1; CP-14185-1.
IUPAC/Chemical Name
1-Piperazinecarboxylic acid, 4-(6,7-dimethoxy-4-quinazolinyl)-, 2-hydroxy-2-methylpropyl ester, monohydrochloride
InChi Key
UGBDUZVYTXIXHU-UHFFFAOYSA-N
InChi Code
InChI=1S/C19H26N4O5.ClH/c1-19(2,25)11-28-18(24)23-7-5-22(6-8-23)17-13-9-15(26-3)16(27-4)10-14(13)20-12-21-17;/h9-10,12,25H,5-8,11H2,1-4H3;1H
SMILES Code
O=C(N1CCN(C2=C3C=C(OC)C(OC)=CC3=NC=N2)CC1)OCC(C)(O)C.[H]Cl
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 426.89 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Greenslade FC, Scott CK, Newquist KL, Krider KM, Chasin M. Heterogeneity of biochemical actions among vasodilators. J Pharm Sci. 1982 Jan;71(1):94-100. PubMed PMID: 6276530. 2: Schach von Wittenau M, Brewer TF. Quinazolines in man. Metabolism and preliminary evaluation of piquizil and hoquizil, two bronchodilators. Pharmacology. 1971;6(3):173-85. PubMed PMID: 4946165. 3: Scillitani B, Thomas J, Brewer TF, Lyons H, Steen SN. Hoquizil--a new oral bronchodilator. A double-blind, randomized, coded clinical study using body plethysmography. Acta Anaesthesiol Scand Suppl. 1969;37:299-302. PubMed PMID: 4912116.