MedKoo Cat#: 525231 | Name: GSK-626616
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Description:

WARNING: This product is for research use only, not for human or veterinary use.

GSK 626616 is a YAK3/DYRK3 kinase inhibitor. It is a chemoprotective agent for the potential treatment of chemotherapy-induced anaemia.

Chemical Structure

GSK-626616
GSK-626616
CAS#1025821-33-3

Theoretical Analysis

MedKoo Cat#: 525231

Name: GSK-626616

CAS#: 1025821-33-3

Chemical Formula: C18H10Cl2N4OS

Exact Mass: 399.9952

Molecular Weight: 401.27

Elemental Analysis: C, 53.88; H, 2.51; Cl, 17.67; N, 13.96; O, 3.99; S, 7.99

Price and Availability

Size Price Availability Quantity
10mg USD 350.00 2 Weeks
25mg USD 650.00 2 Weeks
50mg USD 950.00 2 Weeks
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Related CAS #
No Data
Synonym
GSK-626616; GSK 626616; GSK626616.
IUPAC/Chemical Name
(5Z)-2-(2,6-Dichloroanilino)-5-(quinoxalin-6-ylmethylidene)-1,3-thiazolone
InChi Key
RJPNRXFBYZVRIB-DHDCSXOGSA-N
InChi Code
InChI=1S/C18H10Cl2N4OS/c19-11-2-1-3-12(20)16(11)23-18-24-17(25)15(26-18)9-10-4-5-13-14(8-10)22-7-6-21-13/h1-9H,(H,23,24,25)/b15-9-
SMILES Code
ClC1=C(C(Cl)=CC=C1)NC(S/C2=C\C3=CC=C4N=CC=NC4=C3)=NC2=O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 401.27 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Wippich F, Bodenmiller B, Trajkovska MG, Wanka S, Aebersold R, Pelkmans L. Dual specificity kinase DYRK3 couples stress granule condensation/dissolution to mTORC1 signaling. Cell. 2013 Feb 14;152(4):791-805. doi: 10.1016/j.cell.2013.01.033. PubMed PMID: 23415227.