FR-190809 | CAS#215589-63-2 | ACAT Inhibitor

MedKoo Cat#: 525116 | Name: FR-190809

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FR-190809 is a potent, nonadrenotoxic, orally efficacious ACAT inhibitor.

Chemical Structure

FR-190809

CAS#215589-63-2

Theoretical Analysis

MedKoo Cat#: 525116

Name: FR-190809

CAS#: 215589-63-2

Chemical Formula: C29H34FN3O6S2

Exact Mass: 603.1873

Molecular Weight: 603.73

Elemental Analysis: C, 57.69; H, 5.68; F, 3.15; N, 6.96; O, 15.90; S, 10.62

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.

Bulk Inquiry

Related CAS #

No Data

Synonym

FR-190809; FR 190809; FR190809.

IUPAC/Chemical Name

Urea, N-cycloheptyl-N-((4-(4-fluorophenoxy)phenyl)methyl)-N'-(6-methyl-2,4-bis(methylsulfonyl)-3-pyridinyl)-

InChi Key

UFRBZRWETFGORO-UHFFFAOYSA-N

InChi Code

InChI=1S/C29H34FN3O6S2/c1-20-18-26(40(2,35)36)27(28(31-20)41(3,37)38)32-29(34)33(23-8-6-4-5-7-9-23)19-21-10-14-24(15-11-21)39-25-16-12-22(30)13-17-25/h10-18,23H,4-9,19H2,1-3H3,(H,32,34)

SMILES Code

Cc1cc(c(c(n1)S(=O)(=O)C)NC(=O)N(Cc2ccc(cc2)Oc3ccc(cc3)F)C4CCCCCC4)S(=O)(=O)C

Appearance

Solid powder

Purity

>98% (or refer to the Certificate of Analysis)

Shipping Condition

Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.

Storage Condition

Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).

Solubility

Soluble in DMSO, not in water

Shelf Life

>2 years if stored properly

Drug Formulation

This drug may be formulated in DMSO

Stock Solution Storage

0 - 4 C for short term (days to weeks), or -20 C for long term (months).

HS Tariff Code

2934.99.9001

More Info

Instruction

View handling instruction

Preparing Stock Solutions

The following data is based on the product molecular weight 603.73 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.15 mL	5.76 mL	11.51 mL
5 mM	0.23 mL	1.15 mL	2.3 mL
10 mM	0.12 mL	0.58 mL	1.15 mL
50 mM	0.02 mL	0.12 mL	0.23 mL

1: Tanaka A, Terasawa T, Hagihara H, Ishibe N, Sawada M, Sakuma Y, Hashimoto M, Takasugi H, Tanaka H. Inhibitors of acyl-CoA:cholesterol O-acyltransferase. 3. Discovery of a novel series of N-alkyl-N-[(fluorophenoxy)benzyl]-N'-arylureas with weak toxicological effects on adrenal glands. J Med Chem. 1998 Oct 22;41(22):4408-20. PubMed PMID: 9784116.