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MedKoo Cat#: 525102 | Name: FR 900490

Description:

WARNING: This product is for research use only, not for human or veterinary use.

FR 900490 is a new type of immunoactive substance produced by a fungus Discosia sp. F-11809. The colony forming units in culture (cfu-c) in bone marrow cells, which were suppressed by immunosuppressive factor obtained from the serum of sarcoma 180 tumor bearing mouse, was restored to normal level by the addition of FR-900490 in vitro.

Chemical Structure

FR 900490
FR 900490
CAS#105424-59-7

Theoretical Analysis

MedKoo Cat#: 525102

Name: FR 900490

CAS#: 105424-59-7

Chemical Formula: C14H22N6O6

Exact Mass: 370.1601

Molecular Weight: 370.36

Elemental Analysis: C, 45.40; H, 5.99; N, 22.69; O, 25.92

Price and Availability

This product is currently not in stock but may be available through custom synthesis. To ensure cost efficiency, the minimum order quantity is 1 gram. The estimated lead time is 2 to 4 months, with pricing dependent on the complexity of the synthesis (typically high for intricate chemistries). Quotes for quantities below 1 gram will not be provided. To request a quote, please click the button below. Note: If this product becomes available in stock in the future, pricing will be listed accordingly.
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Related CAS #
No Data
Synonym
FR 900490; FR900490; FR-900490; BMY 28700.
IUPAC/Chemical Name
Butanoic acid, L-asparaginyl-N3-(1-carboxy-2-(1H-imidazol-4-yl)ethyl)-L-threo-2,3-diamino-, (S)-
InChi Key
SJMNSEOOTVHHOW-PBCZWWQYSA-N
InChi Code
InChI=1S/C14H22N6O6/c1-6(19-9(13(23)24)2-7-4-17-5-18-7)11(14(25)26)20-12(22)8(15)3-10(16)21/h4-6,8-9,11,19H,2-3,15H2,1H3,(H2,16,21)(H,17,18)(H,20,22)(H,23,24)(H,25,26)/t6-,8+,9+,11+/m1/s1
SMILES Code
C([C@@H](N[C@@H]([C@H](NC([C@H](CC(=O)N)N)=O)C(=O)O)C)Cc1c[nH]cn1)(=O)O
Appearance
Solid powder
Purity
>98% (or refer to the Certificate of Analysis)
Shipping Condition
Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition
Dry, dark and at 0 - 4 C for short term (days to weeks) or -20 C for long term (months to years).
Solubility
Soluble in DMSO, not in water
Shelf Life
>2 years if stored properly
Drug Formulation
This drug may be formulated in DMSO
Stock Solution Storage
0 - 4 C for short term (days to weeks), or -20 C for long term (months).
HS Tariff Code
2934.99.9001
More Info

Preparing Stock Solutions

The following data is based on the product molecular weight 370.36 Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which will affect the solvent volumes required to prepare stock solutions.

Recalculate based on batch purity %
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 1.15 mL 5.76 mL 11.51 mL
5 mM 0.23 mL 1.15 mL 2.3 mL
10 mM 0.12 mL 0.58 mL 1.15 mL
50 mM 0.02 mL 0.12 mL 0.23 mL
1: Shibata T, Nakayama O, Okuhara M, Tsurumi Y, Terano H, Kohsaka M. A new immunomodulator, FR-900490. J Antibiot (Tokyo). 1988 Sep;41(9):1163-9. PubMed PMID: 3141334.