Alectinib synthetic routes

CAT#: 329490 | Name: Baloxavir marboxil | CAS# 1985606-14-1

Purchases for research

Description:

Baloxavir marboxil is not in stock, may be available through custom synthesis. For cost-effective reason, minimum 1 gram order is requested. The product will be characterized by NMR, HPLC and MS analysis. Purity (HPLC) is usually >98%. CoA, QC data, MSDS will be provided when product is successfully made. The estimated lead time is 2-3 months. Please send email to sales@medkoo.com to inquire quote.

Synthetic Routes

Baloxavir marboxil - Synthetic Route 1

Baloxavir marboxil - Synthetic Route 1

Synthetic reference

Okamoto, Kazuya; Ueno, Tatsuhiko; Hato, Yoshio; Hakogi, Toshikazu; Majima, Shohei. Method for stereoselective preparation of substituted polycyclic pyridone derivative. Assignee Shionogi & Co., Ltd., Japan. WO 2019070059. (2019).

Baloxavir marboxil - Synthetic Route 2

Baloxavir marboxil - Synthetic Route 2

Synthetic reference

Zhu, Xiaoyun; Jiang, Weiping. Process for preparation os substituted polycyclic carbamoylpyridone derivative and its prodrug. CN 108440564. (2018).

Baloxavir marboxil - Synthetic Route 3

Baloxavir marboxil - Synthetic Route 3

Synthetic reference

Kawai, Makoto; Tomita, Kenji; Akiyama, Toshiyuki; Okano, Azusa; Miyagawa, Masayoshi. Pharmaceutical composition containing polycyclic pyridone derivatives as cap-dependent endonuclease (CEN) inhibitors. Assignee Shionogi and Co., Ltd., Japan. JP 6249434. (2017).

Baloxavir marboxil - Synthetic Route 4

Baloxavir marboxil - Synthetic Route 4

Synthetic reference

Shibahara, Setsuya; Fukui, Nobuaki; Maki, Toshikatsu. Polycyclic pyridone derivative, crystal and preparation method thereof. Assignee Shionogi and Co., Ltd., Japan. JP 6212678. (2017).

Baloxavir marboxil - Synthetic Route 5

Baloxavir marboxil - Synthetic Route 5

Synthetic reference

No Data