Alectinib synthetic routes

CAT#: 581388 | Name: Omidenepag Isopropyl | CAS# 1187451-19-9

Purchases for research

Description:

Omidenepag isopropyl is a novel, selective, non-prostanoid EP2 receptor agonist. It can be used for treatment of open-angle glaucoma and ocular hypertension. Omidenepag isopropyl is a prodrug that is converted by hydrolysis of its isopropyl ester to the active metabolite omidenepag.[5] Omidenepag is a selective prostaglandin E2 receptor agonist. It was approved for medical use in Japan in 2018, and in the United States in September 2022.

Synthetic Routes

Omidenepag Isopropyl - Synthetic Route 1

Omidenepag Isopropyl - Synthetic Route 1

Synthetic reference

Preparation of pyridylaminoacetic acids for treatment of respiratory diseases

By: Iwamura, Ryo; et al

World Intellectual Property Organization, WO2009113600 A1 2009-09-17