Balsalazide Disodium is the disodium salt form of balsalazide, an aminosalicylate and oral prodrug that is enzymatically cleaved in the colon to produce the anti-inflammatory agent mesalazine. Mesalazine acts locally on the mucosa of the colon where it diminishes inflammation by blocking the production of arachidonic acid metabolites and other inflammatory agents. Balsalazide disodium is used to treat chronic inflammatory bowel disease.
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Wang, Shaojie; Yao, Juanjuan; Yang, Fuan; Wu, Yuexia; Mu, Qingsu. Preparation of sodium balsalazide. Assignee Shanxi Ante Biological Pharmaceutical Co., Ltd., Peop. Rep. China. CN 101503377. 2009
