MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search

Home  /  Drug Synthesis

Alectinib synthetic routes

Cenobamate - Synthetic Route

CAT#: 319543 | Name: Cenobamate | CAS# 913088-80-9

Purchases for research

Description:

Cenobamate, also known as YKP-3089, is a novel new antiepileptic drug candidate. Cenobamate showed broad-spectrum anticonvulsant activity. Cenobamate entered into clinical trials and was discontinued in 2015.

Synthetic Routes

Cenobamate - Synthetic Route 1

Cenobamate - Synthetic Route 1

Synthetic reference

Lim, Sang Chul; Uhm, Moo Yong; Cho, Nahm Ryune; Lee, Dae Won; Lee, Ju Young; Kim, Hui Ho; Lee, Dong Ho. Preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl esters. Assignee SK Holdings Co., Ltd., S. Korea; SK Biopharmaceuticals Co., Ltd. US 20100323410. (2010).

Cenobamate - Synthetic Route 2

Cenobamate - Synthetic Route 2

Synthetic reference

Lim, Sang Chul; Uhm, Moo Yong; Lee, Dae Won; Kim, Hui Ho; Lee, Dong Ho; Lee, Hyun Seok. Process for preparation of carbamic acid (R)-1-aryl-2-tetrazolyl-ethyl esters. Assignee SK Holdings Co.,Ltd., S. Korea; SK Biopharmaceuticals Co.,Ltd. WO 2011046380. (2011).

Cenobamate - Synthetic Route 3

Cenobamate - Synthetic Route 3

Synthetic reference

Choi, Yong-Moon; Kim, Choon-Gil; Kang, Young-Sun; Yi, Han-Ju; Lee, Hyun-Seok; Ku, Bon-Chul; Lee, Eun-Ho; Im, Dae-Joong; Shin, Yu-Jin. Preparation of triazoles and tetrazoles containing carbamoyl group as anticonvulsants. Assignee SK Corporation, S. Korea. WO 2006112685. (2005).