MedKoo Biosciences, Inc.
Tel:   +1-919-636-5577    Fax:   +1-919-980-4831    Email:   sales@medkoo.com
Search
Login Register
Search

Home  /  Drug Synthesis

Alectinib synthetic routes

Dalfampridine - Synthetic Route

CAT#: 317577 | Name: Dalfampridine | CAS# 504-24-5

Description:

Dalfampridine is a potassium channel blocker used to help multiple sclerosis patients walk. This is the first drug that was specifically approved to help with mobility in these patients. It has been approved by the FDA for use as a treatment for multiple sclerosis.

Synthetic Routes

Dalfampridine - Synthetic Route 1

Dalfampridine - Synthetic Route 1

Synthetic reference

Process for preparation of aminopyridine from methylpyridine; Zhang, Sheng; Zhang, Kuanyu; Jin, Wenyi; Li, Jing Assignee Anhui Xingyu Chemical Co., Ltd., Peop. Rep. China 2017; Patent Information; Aug 04, 2017; CN 107011255 A

Dalfampridine - Synthetic Route 2

Dalfampridine - Synthetic Route 2

Synthetic reference

Baeten, Mattijs; Maes, Bert U. W. Advanced Synthesis & Catalysis; Volume 358; Issue 5; Pages 826-833; Journal; 2016

Dalfampridine - Synthetic Route 3

Dalfampridine - Synthetic Route 3

Synthetic reference

Liao, Rong; Wan, Ji-qiu; Yuan, Xiao-jing. Study on the synthesis of 4-dimethylaminopyridine (DMAP). Xinan Minzu Daxue Xuebao, Ziran Kexueban. Volume 30. Issue 4. Pages 425-428. 2004.

Dalfampridine - Synthetic Route 4

Dalfampridine - Synthetic Route 4

Synthetic reference

Golubeva, G. A.; Popova, A. G.; Vol'pin, I. M. Synthesis and some properties of 4-pyridylhydrazides. Vestnik Moskovskogo Universiteta, Seriya 2: Khimiya. Volume 21. Issue 5. Pages 486-90. 1980.

Dalfampridine - Synthetic Route 5

Dalfampridine - Synthetic Route 5

Synthetic reference

Bobba, Siva Kumar Venkata; Tripathi, Alok Pramod; Kodali, Eswara Rao; Patel, Girish Bansilal; Vaidya, Sanjay Dashrath. A process for the preparation of fampridine. Assignee Enaltec Labs Pvt. Ltd., India. WO 2011108009. (2011).

Dalfampridine - Synthetic Route 6

Dalfampridine - Synthetic Route 6

Synthetic reference

Scholz, U.; Schlummer, B. Arylamines. Science of Synthesis. Volume 31b. Pages 1565-1678. 2007.

Dalfampridine - Synthetic Route 7

Dalfampridine - Synthetic Route 7

Synthetic reference

Guo, Yu-liang; Hu, Xi-en. Process research on the electrosynthesis of 4-aminopyridine. Gaoxiao Huaxue Gongcheng Xuebao. Volume 19. Issue 4. Pages 562-566. 2005.

Dalfampridine - Synthetic Route 8

Dalfampridine - Synthetic Route 8

Synthetic reference

Liao, Rong; Wan, Ji-qiu; Yuan, Xiao-jing. Study on the synthesis of 4-dimethylaminopyridine (DMAP). Xinan Minzu Daxue Xuebao, Ziran Kexueban. Volume 30. Issue 4. Pages 425-428. 2004.

Dalfampridine - Synthetic Route 9

Dalfampridine - Synthetic Route 9

Synthetic reference

Jaime-Figueroa, Saul; Liu, Yanzhou; Muchowski, Joseph M.; Putman, David G. Allyl amines as ammonia equivalents in the preparation of anilines and heteroarylamines. Tetrahedron Letters. Volume 39. Issue 11. Pages 1313-1316. 1998.

Dalfampridine - Synthetic Route 10

Dalfampridine - Synthetic Route 10

Synthetic reference

Golubeva, G. A.; Popova, A. G.; Vol'pin, I. M. Synthesis and some properties of 4-pyridylhydrazides. Vestnik Moskovskogo Universiteta, Seriya 2: Khimiya. Volume 21. Issue 5. Pages 486-90. 1980.