Alectinib synthetic routes

CAT#: 329881 | Name: Sarecycline | CAS# 1035654-66-0

Description:

Sarecycline, also known as WC-3035 and P005672, is a novel, tetracycline-derived, narrow-spectrum antibiotic being developed for use as an oral once daily antibiotic treatment for patients suffering from moderate to severe acne vulgaris. Sarecycline was designed by Paratek as a narrow-spectrum antibiotic with anti-inflammatory activity and the potential for a favorable tolerability profile.

Synthetic Routes

Sarecycline - Synthetic Route 1

Sarecycline - Synthetic Route 1

Synthetic reference

Assefa, Haregewin; Bhatia, Beena; Draper, Michael; Honeyman, Laura; Molnar, Dennis P.; Kim, Oak K. Preparation of substituted tetracycline compounds for treatment of inflammatory skin disorders. Assignee Paratek Pharmaceuticals, Inc., USA. CA 2892739. (2008).