Alectinib synthetic routes

CAT#: 326998 | Name: Revefenacin | CAS# 864750-70-9

Purchases for research

Description:

Revefenacin, also known as TD-4208; GSK-1160724, is a long-acting muscarinic receptor antagonist and may be potentially useful for the treatment of respiratory disease.

Synthetic Routes

Revefenacin - Synthetic Route 1

Revefenacin - Synthetic Route 1

Synthetic reference

Colson, Pierre-Jean. Process for preparing a biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl) benzoyl]methylamino}ethyl)piperidin-4-yl ester. Assignee Theravance, Inc., USA. WO 2012009166. (2012).

Revefenacin - Synthetic Route 2

Revefenacin - Synthetic Route 2

Synthetic reference

Axt, Sabine; Church, Timothy J.; Malathong, Viengkham. Crystalline forms of biphenyl-2-ylcarbamic acid 1-[2-[[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino]ethyl]piperidin-4-yl ester and their salts. Assignee Theravance, Inc., USA. WO 2006099165. (2006).