Migalastat is a potent inhibitor of glycolipid biosynthesis.
Kim, Jin-Seok; Lee, Yong-Taek; Lee, Kun-Hee; Myeong, In-Soo; Kang, Jong-Cheol; Jung, Changyoung; Park, Seok-Hwi; Ham, Won-Hun. Stereoselective Chirality Extension of syn,anti- and syn,syn-Oxazine and Stereochemical Analysis of Chiral 1,3-Oxazines: Stereoselective Total Syntheses of (+)-1-Deoxygalactonojirimycin and (-)-1-Deoxygulonojirimycin. Journal of Organic Chemistry. Volume 81. Issue 17. Pages 7432-7438. Journal; Online Computer File. (2016).
Chacko, Shibin; Ramapanicker, Ramesh. Diastereoselective Synthesis of 1-Deoxygalactonojirimycin, 1-Deoxyaltronojirimycin, and N-Boc-(2S,3S)-3-Hydroxypipecolic Acid via Proline Catalyzed α-Aminoxylation of Aldehydes. Journal of Organic Chemistry. Volume 80. Issue 9. Pages 4776-4782. Journal; Online Computer File. (2015).
McDonnell, Ciaran; Cronin, Linda; O'Brien, Julie L.; Murphy, Paul V. A General Synthesis of Iminosugars. Journal of Organic Chemistry. Volume 69. Issue 10. Pages 3565-3568. Journal. (2004).
Heiker, Fred Robert; Schueller, Alfred Matthias. The chemistry of the 1-deoxynojirimycin system. II. Synthesis of D-galacto-1-deoxynojirimycin (1,5-dideoxy-1,5-imino-D-galactitol) starting from 1-deoxynojirimycin. Carbohydrate Research. Volume 203. Issue 2. Pages 314-18. Journal. (1990).
Legler, Guenter; Pohl, Stefan. Synthesis of 5-amino-5-deoxy-D-galactopyranose and 1,5-dideoxy-1,5-imino-D-galactitol, and their inhibition of α- and β-D-galactosidases. Carbohydrate Research. Volume 155. Pages 119-29. Journal. (1986).
Marjanovic Trajkovic, Jasna; Milanovic, Vesna; Ferjancic, Zorana; Saicic, Radomir N. On the Asymmetric Induction in Proline-Catalyzed Aldol Reactions: Reagent-Controlled Addition Reactions of 2,2-Dimethyl-1,3-dioxane-5-one to Acyclic Chiral α-Branched Aldehydes. European Journal of Organic Chemistry. Volume 2017. Issue 41. Pages 6146-6153. Journal; Online Computer File. (2017).
Chan, Ting-Hao; Chang, Yi-Fan; Hsu, Jung-Jung; Cheng, Wei-Chieh. Straightforward Synthesis of Diverse 1-Deoxyazapyranosides via Stereocontrolled Nucleophilic Additions to Six-Membered Cyclic Nitrones. European Journal of Organic Chemistry. Issue 29. Pages 5555-5559, S5555/1-S5555/73. Journal. (2010).
Jenkinson, Sarah F.; Fleet, George W. J.; Nash, Robert J.; Koike, Yuriko; Adachi, Isao; Yoshihara, Akihide; Morimoto, Kenji; Izumori, Ken; Kato, Atsushi. Looking-Glass Synergistic Pharmacological Chaperones: DGJ and L-DGJ from the Enantiomers of Tagatose. Organic Letters. Volume 13. Issue 15. Pages 4064-4067. Journal; Online Computer File. (2011).
Takahata, Hiroki; Banba, Yasunori; Ouchi, Hidekazu; Nemoto, Hideo. Concise and Highly Stereocontrolled Synthesis of 1-Deoxygalactonojirimycin and Its Congeners Using Dioxanylpiperidene, a Promising Chiral Building Block. Organic Letters. Volume 5. Issue 14. Pages 2527-2529. Journal. (2003).
Attolino, Emanuele; Santillo, Niccolo; Razzetti, Gabriele. Synthesis of migalastat azasugar and the intermediates thereof. Assignee Dipharma Francis S.r.l., Italy. WO 2019020362. (2019).