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Alectinib synthetic routes

Lofexidine - Synthetic Route

CAT#: 599157 | Name: Lofexidine | CAS# 31036-80-3

Purchases for research

Description:

Lofexidine reduces narcotic withdrawal symptoms.

Synthetic Routes

Lofexidine - Synthetic Route 1

Lofexidine - Synthetic Route 1

Synthetic reference

Vartak, Ashish P.; Crooks, Peter A. A Scalable, Enantioselective Synthesis of the α2-Adrenergic Agonist, Lofexidine. Organic Process Research & Development. Volume 13. Issue 3. Pages 415-419. Journal. (2009).

Lofexidine - Synthetic Route 2

Lofexidine - Synthetic Route 2

Synthetic reference

Xu, Zheng; Tang, Weigao; Zhong, Zhicheng. Study on synthetic method of lofexidine hydrochloride. Huaxi Yaoxue Zazhi. Volume 16. Issue 5. Pages 360-361. Journal. (2001).

Lofexidine - Synthetic Route 3

Lofexidine - Synthetic Route 3

Synthetic reference

Biedermann, Juergen; Prop, Gerrit; Doppelfeld, Ille Stephanie. (-)-2-[1-(2,6-Dichlorophenoxy)ethyl]-1,3-diazacyclopent-2-ene and its use in pharmaceutical preparations. Assignee Nattermann, A., und Cie. G.m.b.H., Fed. Rep. Ger. DE 3149009. (1983).